Titanium Desktop – Node.js Prototype « Appcelerator Developer Center. Titanium is already on the list of things to test because, alongside PhoneGap, it is one of the ways to turn JS+HTML code into apps and desktop applications. And here, one of the developers shows how to integrate a node server into the desktop. This would also be quite interesting, although it probably won't work with iOS and Android (since there you are forced to use the JS engine provided by the system in the browser widget if you want to load dynamic code from outside).
Archive 27. March 2012
Embedding and running Node.js within a Firefox XUL extension. Impressive what you can do with Firefox and its infrastructure. Theoretically, you could also modify this extension so that it runs in a single-site browser, which then directly opens the homepage of the embedded server, allowing you to build completely autonomous desktop applications in JavaScript (and for those wondering why I'm collecting all these JS-on-desktop things: with the help of Phonegap and some glue, you could not only build apps for iOS and Android, but also desktop applications with the same code).
NodObjC. I'm not sure if I really want this, but with this library you can bridge ObjC frameworks with JavaScript. This could be interesting, for example, in the context of PhoneGap, if you need to access iOS native APIs that are not yet provided by PhoneGap (though you need Node.js as a basis, I don't know if that already works on iOS).
topcube. I should take a closer look at this - a desktop app that includes an embedded web server (node.js) and browser (GTKWebKit). With this, you can build desktop applications based on JavaScript and Node.js - for example, also rebuild Amber Smalltalk into a compact desktop application. Unfortunately, the OSX support is still somewhat limited.